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Updated: Sep 13, 2025

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
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洞察卡斯帕斯-6突变和神经病理在亨廷顿氏病和精神疾病:一个结构基因组学和药物重定位方法

Mohammed Ageeli Hakami1,2, Ahad Amer Alsaiari3, Ali Hazazi4,5

  • 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Al- Quwayiyah 19257, Riyadh, Saudi Arabia. m.hakami@su.edu.sa.

Molecular neurobiology
|August 1, 2025
PubMed
概括

研究人员确定了与亨廷顿病 (HD) 发病相关的caspase-6 (CASP6) 突变. 他们还发现了两种重新定制的药物,Risperidone和Lorpiprazole,可以抑制CASP6,为HD提供新的治疗途径.

关键词:
生物标志物 生物标志物卡斯帕-6是一种有害的突变 有害的突变药物重新定位是药物重新定位.亨廷顿病就是亨廷顿病.

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