母亲精神病患者入院和儿童发育迟缓:一项全国性的队列研究
Yonatan Bilu1, Guy Amit2, Noa Gueron-Sela3
1KI Research Institute, Kfar Malal, Israel. yonatan@kinstitute.org.il.
Archives of women's mental health
|August 1, 2025
概括
导致精神病患者入院的母亲精神疾病显著增加了儿童发育迟缓的风险. 早期识别和支持面临风险的母婴双对改善结果至关重要.
科学领域:
- 围产期心理健康问题
- 儿童发展 儿童发展
- 精神病学流行病学 精神病学流行病学
背景情况:
- 母亲精神疾病与儿童发育迟缓有关.
- 关于围产期精神病诊所对儿童发育的影响的证据有限.
研究的目的:
- 量化母亲精神病医院入院和儿童发育迟缓之间的关联.
- 探索入院时间,产妇诊断和发育领域如何与延迟有关.
主要方法:
- 对634918名儿童 (1-36个月) 的回顾性队列研究.
- 母亲精神病诊所的入院数据与儿童健康联系,儿童访问记录.
- 根据人口和出生数据进行调整;根据诊断和时间分层的二次分析.
主要成果:
- 母亲精神病诊所的入院与儿童发育迟缓的几率增加有关 (OR ~1.7).
- 精神病障碍,多次入院和儿童第一年入院期间观察到更高的风险.
- 增加的几率即使在较晚的入院中也持续存在,并且在儿童年龄较大时更明显.
结论:
- 接受精神病治疗的母亲的孩子面临更高的发育迟缓率.
- 对于高风险的母婴双胞胎,产前期的支持对于减轻发育风险至关重要.
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