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Updated: Sep 13, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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联合免疫缺陷患者中MALT1功能丧失:一种新的致病变体和免疫学见解

Zhirui Tian1,2, Ran Chen1,2, Yanjun Jia1,2,3

  • 1National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.

Journal of clinical immunology
|August 1, 2025
PubMed
概括

生殖系MALT1缺陷通过破坏NF-kB信号传递导致严重的综合免疫缺陷 (CID). 一种新型的MALT1变异导致免疫细胞功能受损和炎症表型,突显出血造干细胞移植 (HSCT) 的必要性.

关键词:
B细胞的发育过程这是一个CBM复杂的CBM综合体.综合免疫缺陷 (CID) 是一种疾病.马耳他语 马耳他语在 NF-kBB 中,

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