婴儿通过西班牙哺乳母亲的母乳接触金属和风险评估
Carmen Sáez1,2, Alfredo Sánchez1, Pablo Dualde3
1Public Health Laboratory of Alicante, 6 Plaza de España, 03010, Alicante, Spain.
Environmental science and pollution research international
|August 1, 2025
概括
这项研究测量了西班牙母亲的必需和有毒金属.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 人类营养人类营养
背景情况:
- 重金属毒性带来健康风险,其在母乳中的存在加剧了这种风险,母乳是婴儿的关键营养来源.
- 人母乳是婴儿的主要营养来源,因此对重金属等污染物的评估对公共卫生至关重要.
研究的目的:
- 评估西班牙人口母乳中必需和有毒金属的含量.
- 在西班牙,对通过母乳接触有毒金属的婴儿进行风险评估.
主要方法:
- 在母乳样本中量化了七种必需金属 (Co, Cu, Mn, Mo, Se, Zn, V) 和13种有毒金属 (Sb, As, Ba, Be, Cd, Cs, Pb, Hg, Ni, Pt, Th, Tl, U).
- 利用了参加西班牙生物监测项目 (BETTERMILK) 的118名哺乳母亲的数据.
- 每种金属的计算检测频率 (DF) 和几何平均度 (GM).
主要成果:
- 对铜 (Cu), (Zn), (Se) 和 (Cs) 观察到高检测频率 (100%).
- 在93%的样本中检测到 (As),84%的样本中检测到 (Hg);其他元素的DF值为<40%.
- 婴儿通过母乳摄入有毒和必需金属的估计摄入量低于已确定的有毒基准值.
结论:
- 这项研究提供了西班牙通过母乳对婴儿接触关键有毒金属 (Hg,As,Cd,Pb,Se,Zn) 的首次风险评估.
- 根据已确定的参考值,目前母乳中评估的金属含量似乎不会对西班牙新生儿造成重大健康风险.
相关概念视频
Development of Human Microbiota
73
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
73
Development of the Oral Microbiota
75
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
75


