癌症负担和NCI指定的癌症中心当前资金的差异
Todd Burus1, Caree R McAfee1, Pamela C Hull1,2
1Markey Cancer Center, University of Kentucky, Lexington.
JAMA network open
|August 1, 2025
概括
国家癌症研究所为癌症中心提供的资金与流域癌症负担不一致. 资金应考虑癌症负担和弱势群体,以减少差异.
科学领域:
- 癌症研究资金 癌症研究资金
- 在健康方面存在差异.
- 公共卫生政策 公共卫生政策
背景情况:
- 国家癌症研究所 (NCI) 指定的癌症中心定义地理流域 (CA) 进行研究和宣传,以减少癌症负担.
- 缺乏一个全面的分析,将CA癌症负担与癌症中心支持补助金 (CCSG) 资金联系起来.
研究的目的:
- 检查CA内部的癌症负担指标及其与2023财年CCSG资金的关联.
- 评估CCSG资金是否与NCI指定癌症中心的CA中的癌症负担和社会人口统计因素保持一致.
主要方法:
- 这是一项针对64个NCI指定癌症中心的基于人口的横截面研究.
- 分析CA癌症发病率,社会人口统计变量 (种族,种族,社会经济地位,残疾,城市化) 和23财年CCSG资金.
- 斯皮尔曼等级相关性被用来评估癌症负担指标和人口调整后的CCSG资金之间的关联.
主要成果:
- 在CA中观察到癌症负担和社会人口结构的实质性变化.
- 人口调整后的CCSG资金显示与总体癌症率没有关联.
- 资金与农村人口和残疾人有积极的联系,但与种族/少数民族人口有负面的联系.
结论:
- 在癌症中心的收获区之间,癌症负担存在显著的差异.
- 目前的CCSG资金拨款可能无法有效支持为高需要人群服务的癌症中心.
- 将CA癌症负担和脆弱人口数据纳入资金决策可以改善减少癌症差异的努力.
更多相关视频
12:24A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
5.4K
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
372
相关概念视频
Cancer
49.5K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
49.5K
Cancer Survival Analysis
445
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
445
Cancer Stem Cells and Tumor Maintenance
5.0K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
5.0K
Cancer Vaccines
509
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
509
What is Cancer?
11.1K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
11.1K
Adaptive Mechanisms in Cancer Cells
5.9K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.9K
