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Updated: Sep 13, 2025

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
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Published on: July 27, 2017

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人体IAPP纤维的结构反映了膜和pH条件

Venus Singh Mithu1, Karin Giller1, Evgeny Nimerovsky1

  • 1Department of NMR-based Structural Biology, Max Planck Institute of Multidisciplinary Sciences, Göttingen 37077, Germany.

Journal of the American Chemical Society
|August 1, 2025
PubMed
概括

在2型糖尿病中,生理学相关的模型揭示了人类小岛氨基聚 (hIAPP) 纤维的结构. 膜相互作用和细胞外pH对于理解hIAPP聚合和β细胞功能障碍至关重要.

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