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Updated: Sep 13, 2025

Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence
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拓糖酶IIIα控制着端粒的替代延长

Prashant Khandagale1, Yilun Sun2, Daiki Taniyama1

  • 1Developmental Therapeutics Branch & Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

Cell reports
|August 1, 2025
PubMed
概括

替代延长端粒 (ALT) 癌细胞在端粒中使用拓酶III (TOP3A). TOP3A稳定关键复合体并促进ALT标记物,这表明TOP3A是潜在的癌症治疗点.

关键词:
这就是ALT ALT.在 APBs 的搜索中.这里是BLM.科普:分子生物学 分子生物学DPC 是一个DPC.在TERF2中,TERF2是TERF2.在地球上,地球是地球.在TOP3A中排名第一.同类的重组组合.ssTeloCC 的时间端粒是什么意思 端粒是什么意思

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