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Updated: Sep 13, 2025

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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CD4 T细胞疗法通过保持肠道屏障完整性来抵消炎症和衰老

Manuel M Gómez de Las Heras1,2, Elisa Carrasco1,3,4,5, Mario Pérez-Manrique1,2

  • 1Tissue and Organ Homeostasis Program, Centro de Biología Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain.

Science immunology
|August 1, 2025
PubMed
概括

免疫系统下降,特别是T细胞功能障碍,破坏肠道微生物群和屏障完整性,加速衰老. 恢复T细胞功能促进肠道健康,并延长小鼠的健康寿命.

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