优先考虑国家进行结核病疫苗准备研究,采用以全球利益相关者为中心的方法
Michelle M Gill1, Rupali Limaye2,3, Puck T Pelzer4
1Elizabeth Glaser Pediatric AIDS Foundation, Washington, DC, United States of America.
PLOS global public health
|August 1, 2025
概括
研究人员使用利益相关者的意见优先考虑了结核病 (TB) 疫苗准备研究的国家. 高结核病负担和政治意愿是指导公平疫苗部署战略的关键因素.
科学领域:
- 全球健康 全球健康
- 疫苗学 疫苗学 疫苗学
- 卫生系统研究 卫生系统研究
背景情况:
- 新的结核病 (TB) 疫苗候选人需要对需求和卫生系统准备有效部署进行研究.
- 优先考虑国家对结核病疫苗准备研究,对于公平的全球卫生战略至关重要.
研究的目的:
- 开发和应用一种方法来优先考虑国家进行结核病疫苗准备研究.
- 将利益相关者的偏好与客观数据相结合,以实现透明的国家选择.
主要方法:
- 使用一种混合方法,结合最佳-最差扩展 (BWS) 和分析层次过程 (AHP).
- 对结核病疫苗利益相关者进行的一项调查确定了国家优先考虑的17个标准.
- 公开可用的数据与标准权重相结合,生成国家分数.
主要成果:
- 全国结核病负担和政治意愿是利益相关者确定的最重要的标准.
- 卫生系统的强度和成年人COVID-19疫苗接种覆盖率也是重要因素.
- 获得最高分数的国家主要在撒哈拉以南非洲地区,选择是为了确保区域多样性.
结论:
- AHP-BWS方法提供了一个实用和透明的框架,用于优先考虑结核病疫苗准备研究的国家.
- 这种方法可以为全球公共卫生倡议提供基于证据的资金决策.
- 优先考虑的努力支持公平有效地部署未来的结核病疫苗.
相关概念视频
International Nursing Organizations II
1.1K
The World Health Organization (WHO) is a specialized agency of the United Nations based in Geneva. The WHO has many initiatives that center around health. Primarily, they lead global efforts to expand universal health coverage using science-based policies and programs. They are also responsible for shaping health research agendas and developing norms and standards.
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...
1.1K
Pulmonary Tuberculosis IV
206
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
206
Pulmonary Tuberculosis V
239
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
239
Primary Healthcare Services
1.5K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.5K
Principles of Disease Surveillance
182
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
182
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
176
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
176


