在接受导管心脏干预和心脏起器植入的狗中进行抗菌预防 - 一项调查
Iris L Blok1, Mark Rishniw2, J Scott Weese3
1Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, Utrecht 3584 CM, the Netherlands.
Veterinary microbiology
|August 1, 2025
概括
兽医在使用抗微生物预防药物进行狗心脏干预方面显示出显著的差异,往往超过人类指导方针. 这种不一致的使用缺乏证据,需要为合理的抗菌药物管理制定新的指导方针.
科学领域:
- 兽医心脏病学 兽医心脏病学
- 抗微生物药物管理管理
背景情况:
- 没有确立的指导方针存在用于预防性抗微生物在犬的透血管心脏干预的使用.
- 抗微生物药物耐药性需要通过合理的指示和服用时间来优化抗微生物药物的使用.
研究的目的:
- 调查当前在兽医中预防性抗菌药物使用的现实做法,这些兽医在狗身上进行血管外心脏干预.
- 为了识别协议,药物选择和施用途径/持续时间的变化.
主要方法:
- 一个数字调查被分发给国际兽医心脏病学兴趣小组.
- 141名受访者报告了他们对各种心脏手术的抗菌预防方案.
主要成果:
- 报道了各种方案的广泛变化,仅用于心脏起器植入的47种不同的方案.
- 抗微生物预防经常用于 (89-96%) PDA 阻塞,气球膜整形,支架和起器植入等手术.
- 抗微生物药物使用的平均持续时间为7天 (范围:0-21天),通常比人类医学更长.
- 只有30%的受访者有机构指导方针,这也显示出很大的差异.
结论:
- 在心脏干预中用于抗微生物预防的兽医实践缺乏一致性和基于证据的支持.
- 目前的使用往往超过了人类医学中观察到的持续时间,可能导致抗菌素耐药性.
- 迫切需要重新评估当前的做法,并制定基于证据的指导方针,以合理使用抗微生物药物在犬类干预心脏病学.
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