随着年龄的增长,句子理解中的额头活化增加反映了效率低下,而不是补偿
Maxime Perron1, Hannah Shatzer1, Michael Zara1
1Department of Psychology, Toronto Metropolitan University, Toronto, Ontario, Canada.
Neurobiology of aging
|August 1, 2025
概括
老年人听到噪音时表现出前额叶皮层 (PFC) 活动的增加,这表明神经效率低下而不是补偿. 这种过度激活会导致与年龄相关的语言理解困难,特别是听力较差或认知功能较差的人.
科学领域:
- 神经科学是一个神经科学.
- 认知老龄化 认知老龄化
- 听觉感知是一种听觉感知.
背景情况:
- 认知衰老通常涉及额前皮层 (PFC) 活动的增加.
- 这种PFC活动的增加是有争议的:是补偿性的还是低效的.
- 它在语音噪音 (SiN) 感知中的作用尚不清楚,因为研究结果各不相同.
研究的目的:
- 在SiN理解过程中调查PFC活性与年龄相关的差异.
- 确定增加PFC活动是否有助于或阻碍老年人SiN表现.
主要方法:
- 使用功能近红外光谱 (fNIRS) 来测量PFC活动.
- 57名参与者 (22名年轻人,35名老年人) 在噪音中听到句子.
- 操纵的信号噪声比 (SNR) 和单词可预测性.
主要成果:
- 老年人显示PFC活性增加,SNR下降;年轻人没有.
- 表现较差的老年人有较大的右侧PFC活动.
- 错误的反应与两组中双边PFC活动的增加有关.
- 双边PFC活动增加部分解释了与年龄相关的性能下降.
结论:
- 研究结果支持神经效率低下为认知衰老的框架.
- 过度激活PFC有助于与年龄相关的SiN困难.
- 解决PFC过度激活可能会改善老年人的SiN通信.
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