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Updated: Sep 13, 2025

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HMGB1激活caspase-1并通过GABPA-ASC诱导肝星细胞激活

Mengjia Jing1, Yixing Luo2, Lumiao Zhang1

  • 1Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Biochimica et biophysica acta. Molecular cell research
|August 1, 2025
PubMed
概括

高流动性组盒1 (HMGB1) 通过激活肝星细胞 (HSCs) 来驱动肝纤维化. 抑制HMGB1或caspase-1激活显著逆转肝纤维化进展,突出了一个关键的治疗标.

关键词:
在ASC中,ASC是ASC.在Caspase-1中,在GABPA GABPA中,我们可以看到.这就是HMGB1的特点.炎症 炎症是一种炎症.肝脏纤维化 肝脏纤维化

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