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Updated: Sep 13, 2025

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工业VH2O2杀菌应用的设备和工艺验证:海报在2025年PDA周发布

Mary Van Gaasbeck Carico1

  • 1Life Sciences Equipment and Service - STERIS Corporation, Stoneville, NC, USA mary_vangaasbeck@steris.com.

PDA journal of pharmaceutical science and technology
|August 1, 2025
PubMed
概括

蒸发过氧化 (VH2O2) 低温灭菌对于敏感的医疗器械,如预填注射器,是有效的. 这种方法正在获得监管支持,加强其在制药制造和设备灭菌中的使用.

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In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
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As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
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Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
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