乳腺生物库标本的系统收集中的选择偏差
Yael Bar1,2, Gary X Wang3,4, Gabrielle E Gioia5
1Massachusetts General Hospital Cancer Center, Boston, MA, USA. yael.b@tlvmc.gov.il.
NPJ breast cancer
|August 1, 2025
概括
乳腺癌生物银行招聘显示差异. 老年患者和不说英语的人不太可能被接近. 非西班牙裔白人患者比其他群体更有可能同意.
科学领域:
- 在瘤学瘤学.
- 这是生物银行.
- 健康差异 在健康上的差异
背景情况:
- 乳腺活检组织生物库对于癌症研究至关重要.
- 生物库中不同种群的代表性不足限制了研究的概括性.
- 评估生物银行的招聘差异对于公平的研究至关重要.
研究的目的:
- 评估机构乳腺活检组织银行招聘过程中的潜在差异.
- 为了确定患者子组,不太可能被接近或同意参与生物银行.
主要方法:
- 超声导向 (USG) 研究活检核收集了2019年1月至2022年10月的临床后活检.
- 符合条件的患者被邀请参加放射科医生的裁量权.
- 数据分析了影响接触和同意率的因素,包括年龄,母语,保险,种族和种族.
主要成果:
- 在1309名符合条件的患者中,有886人 (67.7%) 接受了治疗,有564人 (63.7%) 同意接受治疗.
- 70岁以上的患者和拥有非商业保险的非英语说者不太可能被接近.
- 非西班牙裔白人患者比其他群体更有可能同意;非西班牙裔黑人患者特别不太可能同意.
结论:
- 在乳腺活检生物库招聘方面存在显著差异.
- 需要有针对性的干预措施来改善代表性不足的患者子组的参与.
- 解决这些差异对于公平和普遍的乳腺癌研究至关重要.
相关概念视频
Bias in Epidemiological Studies
683
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
683
Bias
4.9K
Bias refers to any tendency that prevents a question from being considered unprejudiced. In research, bias occurs when one outcome or answer is selected or encouraged over others in sampling or testing. Bias can occur during any research phase, including study design, data collection, analysis, and publication.
In statistics, a sampling bias is created when a sample is collected from a population, and some members of the population are not as likely to be chosen as others (remember, each member...
In statistics, a sampling bias is created when a sample is collected from a population, and some members of the population are not as likely to be chosen as others (remember, each member...
4.9K
Systematic Sampling Method
11.1K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
Systematic sampling is one of the simplest methods...
Systematic sampling is one of the simplest methods...
11.1K


