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Updated: Sep 13, 2025

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis ALS
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Published on: March 17, 2012

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该CCL2-CCR2轴驱动的神经肌肉缩在肌缩性侧面硬化症

Bernát Nógrádi1,2,3,4, Kinga Molnár4, Rebeka Kristóf4

  • 1Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh, UK.

Nature communications
|August 1, 2025
PubMed
概括

免疫细胞通过CCL2-CCR2通路透到肌肉神经结节,从而导致肌缩性侧面硬化症 (ALS) 的发生. 准这个轴可能会防止ALS患者的NMJ化.

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