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Updated: Sep 13, 2025

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肠道CD4-CD8αβ-TCRαβ+ T细胞在小鼠中充当耐受性抗原呈现细胞的功能

Yasuhiro Nemoto1,2, Ryo Morikawa3, Yuki Yonemoto3

  • 1Department of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan. ynemoto.gast@tmd.ac.jp.

Nature communications
|August 1, 2025
PubMed
概括

肠道中的双阴性T (DNT) 细胞捕获光线抗原并迁移到淋巴结,通过MHC-II.II呈现它们. 这一过程维持了肠道的免疫耐受性,缺陷可能与炎症性肠病有关.

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