创伤后应激障碍与怀孕结果之间的关联:系统审查和元分析
Natalie M Zitoun1, M Karen Campbell1,2,3,4,5, Joel Gagnier1,5,6
1Department of Epidemiology & Biostatistics, University of Western Ontario, London, ON, Canada.
BMC pregnancy and childbirth
|August 1, 2025
概括
怀孕期间的孕产妇创伤后应激障碍 (PTSD) 与婴儿的不良结果有关,包括降低出生体重和早产. 早期干预和预防PTSD对于改善母亲和新生儿健康至关重要.
科学领域:
- 生殖健康 生殖健康
- 围产期心理健康 围产期心理健康
- 新生儿结局的结果.
背景情况:
- 创伤后应激障碍 (PTSD) 是一种严重的心理健康状况,影响了许多女性.
- 怀孕期间的PTSD可能是产科并发症和新生儿不良后果的潜在因素.
研究的目的:
- 系统地审查和元分析母亲PTSD与怀孕,产科和新生儿结局之间的关联.
主要方法:
- 在多个数据库 (谷歌学者,PubMed,EMBASE) 进行了全面的文献搜索.
- 包括专注于围产期PTSD的研究,并评估了怀孕,产科和新生儿的结果.
- 分析使用了随机效应模型,根据GRADE指南评估证据.
主要成果:
- 审查了40项研究 (157,708例怀孕);其中11,750例显示PTSD症状.
- 母亲的PTSD与婴儿头部周长较小,养问题,母乳养减少和婴儿皮质醇降低有关.
- 分析显示,低出生体重 (OR 2.05) 和早产 (OR 1.23) 的风险增加,尽管证据质量较低.
结论:
- 与怀孕相关的PTSD与不良的孕产妇和新生儿结果有关.
- 在怀孕期间预防和治疗PTSD对于孕产妇,产科和新生儿的健康至关重要.
- 需要进一步研究怀孕治疗PTSD的影响.
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