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Updated: Sep 13, 2025

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网络控制理论揭示了三角神经疼痛中异常的连接体可控性

Tiantian Chu¹, Juan Peng², Feng Gao¹

¹Department of Anesthesiology, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The journal of headache and pain

|August 2, 2025

概括

三神经疼痛 (TN) 显示了大脑网络控制的改变,效率降低和能量需求增加. 这些网络变化是特有的TN和不同于正常的老化效应.

科学领域:

神经科学是一个神经科学.
网络科学网络科学
医疗成像医学成像

背景情况:

三神经疼痛 (TN) 涉及广泛的神经网络变化.
网络控制理论 (NCT) 量化了大脑网络架构对神经动态的影响.

研究的目的:

调查跨境网络中的结构网络可控性.
确定大脑网络控制属性的疾病特异性变化.

主要方法:

在82名TN患者和42名健康对照人群 (HCs) 中进行扩散张力成像.
使用Brainnetome地图库进行结构连接体的构建和分片.
在多个层面计算平均可控性 (AC) 和模式可控性 (MC).

主要成果:

与HC相比,TN患者的全脑AC减少,MC增加.
在背部注意力和默认模式网络中观察到AC降低和MC增加.
在TN患者中发现了显著的年龄控制相关性,与HC不同.

结论:

太阳网表现出异常的网络可控性,影响了状态过渡效率和控制能.
在TN中独特的年龄控制性关系表明疾病特异性网络动态.
NCT是理解TN病理生理学作为网络层次疾病的一个有价值的框架.

关键词:

大脑网络大脑网络可以控制的可控性.扩散张力成像的成像方法网络控制理论网络控制理论结构性的连接性结构性的连接性三胞胎神经疼痛三胞胎神经疼痛

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