全球卫生脱殖:非洲追求制药主权
Moses Mulumba1, Jessica Oga2, Nana Koomson3
1Afya na Haki, Kampala, Uganda.
BMC health services research
|August 2, 2025
概括
非洲正在推动制药主权以本地化药物和疫苗生产,克服殖民遗产和知识产权障碍. 关键的机会包括监管协调,聚合需求和技术转让伙伴关系,以实现一个有弹性的工业未来.
科学领域:
- 全球健康 全球健康
- 制药科学 制药科学
- 卫生政策与经济 卫生政策与经济
背景情况:
- 非洲历史上对进口药品的依赖源于殖民实践和限制性知识产权 (IP) 制度.
- COVID-19大流行凸显了非洲大陆的脆弱性,催化了朝着制药主权的运动.
- 这涉及到通过本地化研究,监管和生产药物和疫苗来实现全球健康的非殖民化.
研究的目的:
- 审查目前关于阻碍非洲制药转型的障碍的证据.
- 确定可以加速本地化工作的监管,金融,技术和公民机会.
- 为实现整个非洲大陆制药主权的战略提供信息.
主要方法:
- 进行了批判性叙事文学评论.
- 在六个数据库 (PubMed,Scopus等) 中进行搜索. 和非洲联盟 (AU) 机构的灰色文献进行了.
- 对包括的45份文件进行反思性主题分析,确定了关键障碍和启用途径.
主要成果:
- 确定了四个主要障碍:符合TRIPS的专利独家权,分散的监管能力,长期的投资不足和偏向进口的采购.
- 补偿机会包括非洲药物管理局 (AMA) 领导的协调,聚合需求工具,技术转让伙伴关系和公民部门动员.
结论:
- 非洲拥有基础要素 - - 监管框架,需求聚合激励措施和技术平台 - - 以本地化制药生产.
- 实现需要同步努力:缓解知识产权约束,完成AMA监管融合,确保API/批量药物能力的融资,并改革采购.
- 这些步骤可以将制药主权转变为可持续的工业现实,推动非洲在全球卫生领域的非殖民化议程.
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