电子尼古丁输送系统与牙腐烂之间的关联:通过元分析进行系统性审查
Matheus Dos Santos Fernandez1, Francisco Wilker Mustafa Gomes Muniz1, Felipe Gomes Dallepiane2
1Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil.
Archives of oral biology
|August 2, 2025
概括
电子尼古丁输送系统 (ENDS) 的使用可能与牙的更高风险有关. 然而,目前的证据有限,确定性非常低,没有发现成人疾病严重程度的显著关联.
科学领域:
- 口腔健康研究 口腔健康研究
- 公共卫生 公共卫生
- 尼古丁产品研究 尼古丁产品研究
背景情况:
- 电子尼古丁输送系统 (ENDS) 的使用在青少年和成年人中很普遍.
- ENDS对口腔健康的影响,特别是牙损,需要进一步研究.
研究的目的:
- 探索ENDS使用与青少年和成人牙损伤之间的关联.
- 评估关于这种关联的偏见风险和证据确定性.
主要方法:
- 在六个数据库中进行系统的文献搜索.
- 包括16岁以上的参与者参与的研究,通过临床/放射性方法评估ENDS使用和.
- 偏见风险评估使用乔安娜·布里格斯研究所检查清单和纽卡斯尔-太华尺度;元分析和GRADE方法用于证据确定性.
主要成果:
- 包括四项研究,其中三项表明ENDS使用与牙损经验或风险之间存在潜在联系.
- 三项研究具有高偏差风险.
- 两项研究的元分析发现,ENDS用户和非用户之间的病史没有显著差异 (MD:0.72,95% CI:-1.70-3.15).
结论:
- 在使用ENDS和增加牙腐烂风险和严重程度之间存在潜在的关联.
- 定量分析没有支持ENDS使用与成年人病严重程度之间的关联.
- 对定性和定量发现的证据的确定性被确定为非常低.
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