对Ag纳米颗粒在宿主寄生生物体中的生物积累和迁移的超结构性表征
Fuad Rzayev1, Eldar Gasimov2, Ali Nasirov3
1Department of Electron Microscopy, Scientific Research Center, Azerbaijan Medical University, Baku, Azerbaijan; Laboratory of Parasitology, Institute of Zoology, Ministry of Science and Education, Baku, Azerbaijan.
Veterinary parasitology
|August 2, 2025
概括
银纳米粒子在寄生虫Heterakis dispar中生物积累,导致病理并在宿主中迁移. 这些纳米粒子还在身上引起了损伤.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 纳米技术 纳米技术
背景情况:
- 纳米粒子生物积累和生态毒性是关键的研究领域.
- nematode Heterakis dispar 线虫会对家用造成很大的伤害.
研究的目的:
- 研究银纳米颗粒 (Ag NPs) 在和H. dispar. 寄生虫宿主系统中的生物积累和迁移.
- 评估AgNP对寄生虫和宿主组织的病理影响.
主要方法:
- 使用光和电子显微镜检查Ag NP分布.
- 应用了组织学方法来分析寄生虫和宿主组织 (肠道,肝脏,骨肌肉).
- 对受感染的施用AgNP,其度为100μg/ml.
主要成果:
- 发现AgNP在H. dispar寄生虫中生物累积,尺寸高达14nm.
- AgNP从寄生虫的整体组织迁移到它的伪骨腔中.
- 在的肠道,肝脏和骨肌肉中观察到病理变化,Ag NPs进入宿主红细胞并迁移到器官.
结论:
- 银纳米粒子积聚在内,并导致线虫 Heterakis dispar. 病变.
- AgNP可以通过寄生虫迁移到宿主的循环系统中,影响重要器官.
- 这项研究强调了纳米粒子暴露在宿主寄生虫生态环境中的潜在风险.
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