隐藏的风险:未知的生物毒性和抗生素耐药性在基于酸的先进废水处理技术中传播
Gong Chen1, Xiao Qiu1, Jingjing Guo1
1State Key Laboratory of Advanced Environmental Technology, Department of Environmental Science and Engineering, University of Science and Technology of China, Hefei 230026, China.
Water research
|August 2, 2025
概括
酸 (PAA) 废水处理增加了抗生素耐药性. 然而,PAA-高级氧化过程 (PAA-AOP) 有效地降低了抗生素耐药性基因和生物毒性,为更清洁的水提供了更安全的解决方案.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 水处理 处理水的方法
背景情况:
- 废水中的抗生素耐药性是一个日益严重的全球健康问题.
- 先进的废水处理旨在改善废水质量,但可能会忽视生物毒性和耐药性传播.
- 甲酸 (PAA) 用于先进的二次废水处理.
研究的目的:
- 研究基于酸 (PAA) 的工艺对先进的二次废水处理中抗生素耐药性的影响.
- 为了比较单独的PAA与基于PAA的先进氧化过程 (PAA-AOP) 在缓解抗生素耐药性和生物毒性方面的疗效.
主要方法:
- 对PAA和PAA-AOP在细菌无活化,细胞外ARG (eARG) 释放和废水中的水平基因转移 (HGT) 的评估.
- 评估与PAA治疗相关的环境生物毒性和基因毒性.
- 使用PAA-AOP测试膜流通系统,以检测抗生素和ARG去除.
主要成果:
- PAA 禁活了细菌,但增加了 eARG 释放和 HGT 频率,同时还诱导了生物毒性和基因毒性.
- PAA-AOP显著降低了细胞内和细胞外ARG (2-4日志降低),并抑制了ARG转移 (大约). 这是十倍的).
- PAA-AOP清除了抗生素的毒素,减少了对水生生物的伤害,并在转合剂中减少了致病细菌.
结论:
- 基于PAA的先进废水处理需要仔细考虑,因为可能会增加抗生素耐药性.
- PAA-AOP是一种有前途的技术,可以同时减少废水中的抗生素耐药性基因和生物毒性.
- 开发的PAA-AOP膜系统在抗生素和ARG去除方面表现出色,为更安全的水生生态系统做出了贡献.
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