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Updated: Sep 13, 2025

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作为生物有机抗癌剂的bufadienolides:对细胞亡,细胞循环停止和信号通路调节的机制性见解

Hector Hernández-Parra1, Sheila Iraís Peña-Corona2, Juan Isaac Chávez-Corona3

  • 1Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de Mexico, Ciudad de México 04510, Mexico; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Ciudad de México, Mexico.

Bioorganic chemistry
|August 2, 2025
PubMed
概括

布法迪化物通过向多种癌症机制,显示出作为抗癌药物的潜力. 然而,像可溶性和毒性差等挑战需要先进的药物输送系统才能获得临床成功.

关键词:
抗癌机制 抗癌机制细胞灭亡 (apoptosis) 是一种死亡的过程.生物可用性 生物可用性布法二烯化物 是一种药物输送是药物输送的过程.信号通道的信号通道.

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