根据SCORE2和SCORE2-OP心血管风险表计算血管年龄
Jose I Cuende1, Carlos Guijarro2
1Department of Medicine, Dermatology and Toxicology, University of Valladolid, Spain.
概括
根据SCORE2和SCORE2-OP风险得分开发出新的血管年龄表. 现在可以在所有欧洲国家使用单一的,通用的血管年龄表来评估心血管风险.
科学领域:
- 评估心血管疾病风险评估
- 公共卫生 公共卫生
- 预防性心脏病学 预防性心脏病学
背景情况:
- 在欧洲心血管指南中,SCORE2和SCORE2-OP风险表 (2021) 取代了旧的SCORE表.
- 血管年龄是一个概念,在2012年推出,以前缺乏表源于新的SCORE2/SCORE2-OP风险算法.
- 现有的血管年龄工具与当前的欧洲心血管风险分层不一致.
研究的目的:
- 根据SCORE2和SCORE2-OP心血管风险预测模型开发新的血管年龄表.
- 根据当前的欧洲指导方针,为评估血管年龄提供最新的工具.
- 为了解决缺少血管年龄表,这些表是从最新的心血管风险评估工具中获得的.
主要方法:
- 使用SCORE2/SCORE2-OP数据计算了基线和非基线条件的年龄和心血管风险之间的回归,跨性别和风险区域.
- 通过将风险表框中的风险与基线条件等同来确定血管年龄.
- 使用回归,确定和类内相关系数评估调整和协议.
主要成果:
- 为低,中等,高和非常高的心血管风险国家开发了四个不同的血管年龄表.
- 在四个表中证明了高一致性 (>0.99),使得可以创建一个通用的血管年龄表.
- 证实了血管年龄,与绝对风险不同,不需要校准.
结论:
- 成功创建了由SCORE2和SCORE2-OP风险分层工具衍生的血管年龄表.
- 一个单一的,通用的血管年龄表适用于所有欧洲国家.
- 这些新的表格为欧洲人口的血管年龄评估提供了一种标准化的方法.
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