延迟手术的选择 - 有证据表明,延迟生殖器官整形在性别发育的差异/障碍方面存在?
Hedvig Engberg1, Lisa Örtqvist2, Gundela Holmdahl2
1Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Medical Unit of Gynaecology and Reproductive medicine, Karolinska University Hospital, Stockholm, Sweden.
概括
推迟生殖器手术的性别发展差异/障碍 (DSD) 是复杂的. 目前对早期或延迟的DSD手术的证据有限,需要进一步研究青春期定时基因整形.
科学领域:
- 医学科学 医学科学 医学科学
- 手术创新 在外科创新.
- 儿科内分泌学 儿科内分泌学
背景情况:
- 性发育差异/障碍 (DSD) 存在复杂的临床挑战.
- 在DSD中,生殖器手术的时间是一个有着重大影响的争论的话题.
- 目前支持早期或延迟手术干预的证据被认为是不够的.
研究的目的:
- 审查关于延迟生殖器外科手术在DSD中的好处的结果研究.
- 探索在青春期开始后进行生殖器造形术的可行性.
- 批判性地评估DSD个体的手术时间选择.
主要方法:
- 对过去二十年的结果研究进行系统审查.
- 关于青春期后个体的生殖器官整形术的文献分析.
- 评估早期与延迟手术方法的证据质量.
主要成果:
- 目前支持DDS早期或延迟的生殖器手术的证据很差.
- 延迟生殖器手术可能会带来潜在的好处,需要进一步调查.
- 在青春期开始后进行生殖器切除术的可行性正在被探索.
结论:
- 在DSD中进行生殖器手术的最佳时间仍然不确定,因为证据有限.
- 需要进一步进行高质量的研究,以指导DSD的临床决策.
- 探索青春期定时干预措施对于改善DSD护理结果至关重要.
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