评估美国农村地区HPV相关癌症的交叉变异
Jason Semprini1, Gabriel Benavidez2, Whitney E Zahnd3
1Department of Public Health, Des Moines University College of Health Sciences, 8025 Grand Ave, West Des Moines, IA, 50266, USA. jsemprini@dmu.edu.
BMC public health
|August 3, 2025
概括
人类乳头瘤病毒 (HPV) 相关的癌症发病率在美国农村社区因种族/种族而异. 干预措施必须解决差异,特别是在高贫困地区的美洲印第安人/阿拉斯加土著人口.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 人类乳头瘤病毒 (HPV) 相关癌症的发病率正在美国农村社区上升.
- 在HPV相关的癌症中,正在出现越来越大的农村和城市差异,农村的交叉性研究不足.
- 这项研究调查了农村地区与HPV相关的癌症发病率,重点关注种族/民族差异.
研究的目的:
- 通过种族/种族对男性和女性来检查农村社区的HPV相关癌症发病率.
- 根据癌症类型,社会经济地位和地理因素来探索这些差异的变化.
主要方法:
- 利用了来自北美中央癌症登记处协会 (NAACCR) 的年龄调整癌症发病率 (2010-2019).
- 专注于农村县的与HPV相关的癌症 (宫癌,阴道癌,阴道癌,阴茎癌,门癌,口癌).
- 按性别,种族/族裔,年龄,癌症部位,贫困,社会经济地位和地区进行分层分析.
主要成果:
- 农村HPV相关癌症的总体发病率为每10万人口中的11.8例 (2010-2019).
- 观察到显著的异质性:男性率 (10.5) 在非西班牙裔白人中最高 (11.2);女性率 (13.2) 在非西班牙裔黑人 (13.8) 和美洲印第安人/阿拉斯加土著人 (14.5) 的人口中最高.
- 种族/民族差异在农村亚群,地理和贫困水平上有所不同.
结论:
- 认识到农村癌症负担的多样性对于开发有效的公共卫生干预措施至关重要.
- 需要有针对性的战略来减少农村人口中与HPV相关的癌症差异.
- 优先考虑对高贫困农村地区的美洲印第安人/阿拉斯加土著人口的干预是必不可少的.
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