早期成年人群体质量指数和近期体重增加在减少癌症幸存者死亡风险方面的协同效应
Yalan Liu1, Hua Zong1, Ying Luo2
1Nanan District Center for Disease Control and Prevention, Chongqing, China.
Nutrition and cancer
|August 3, 2025
概括
最近癌症幸存者的体重增加与较低的死亡风险有关. 在癌症治疗后,体重指数 (BMI) 适度增加可能会改善生存结果.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 癌症幸存者有更高的死亡风险.
- 身体质量指数 (BMI) 的变化可能是癌症幸存者的重要预后因素.
研究的目的:
- 研究早期成年期和近年来BMI变化与癌症特异性和癌症幸存者的全因死亡率之间的关联.
- 探索剂量反应关系和BMI变化对死亡率的值影响.
主要方法:
- 利用了来自国家健康和营养检查调查的数据.
- 采用统计模型来分析BMI变化和死亡结果之间的关联.
- 评估了剂量反应关系,并确定了BMI变化的值效应.
主要成果:
- 最近的BMI增加显着与减少癌症和全因死亡率有关.
- 最近更大的BMI增加 (与最低的三位数相比) 显示,癌症死亡率的风险降低了24%-44%,全因死亡率的风险降低了34%-45%.
- 发现了一个非线性关联,BMI增加5%作为值,每个1%的值低于这个值,死亡风险降低4%.
结论:
- 最近适度体重增加可能会提高癌症幸存者的生存率.
- 个性化体重管理策略对于提高这一群体的生存率至关重要.
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