多发性硬化症患者饮食修改的发生率:系统性审查和元分析
Farnoosh Shemirani1, Tyler J Titcomb2
1Department of Internal Medicine, Division of General Internal Medicine, University of Iowa, Iowa City, IA.
Multiple sclerosis and related disorders
|August 3, 2025
概括
饮食修改在患有多发性硬化症 (MS) 的人群中很常见. 这项系统性审查发现,超过20%的多发性硬化症患者在某个时候改变了饮食.
科学领域:
- 神经学 神经学
- 营养学 营养学 营养学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病.
- 患有多发性硬化症的患者经常探索改变生活方式,包括饮食,以控制症状和改善幸福感.
- 患有多发性硬化症的人群中饮食修改的患病率在很大程度上仍未得到量化.
研究的目的:
- 确定多发性硬化症患者中饮食修改的流行率.
- 分析影响MS中饮食修改患病率的因素.
主要方法:
- 在四个主要数据库中进行了系统的文献审查.
- 纳入标准侧重于对MS成年人报告饮食修改流行率的研究.
- 进行随机效应元分析和子组分析以评估流行率和异质性.
主要成果:
- 该审查分析了39项研究,包括48104名患有MS的参与者.
- 终身饮食修改的流行率为22%,目前的修改率为17%.
- 观察到很高的异质性,受地区,调查日期,样本大小和偏差风险的影响.
结论:
- 饮食修改是患有多发性硬化症的个体中普遍存在的行为.
- 在北美,大洋洲和国际队列中发现了最高的患病率.
- 随着时间的推移,人们观察到饮食修改的趋势越来越大.
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