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Updated: Sep 13, 2025

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焦点粘附激酶驱动Rho/ROCK和mTOR信号,以保护和增加大动脉解剖

Zhen Zhou1, Pujun Guan1, Ripon Sarkar1

  • 1Division of Medical Genetics, Department of Internal Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas, USA.

JACC. Basic to translational science
|August 3, 2025
PubMed
概括

焦点粘附 (FAs) 中的功能障碍机械感知驱动胸前大动脉剖析. FA 激酶,Rho/ROCK 和 mTOR 途径在上升与下降剖析中具有不同的作用,而 mTOR 在上升的大动脉中具有病原性.

关键词:
在Rho/ROCK的基础上.大动脉切割剖析.细胞外矩阵是细胞外矩阵.焦点粘附激酶的焦点粘附激酶.lysyl 氧化酶的作用是什么在mTOROR中使用mTOR.

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