术前大动脉的高阿加斯顿分数导致术后高输出型静脉静脉切除术
Yusuke Kono1, Manabu Yamamoto1, Chiharu Yasui1
1Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
The Journal of surgical research
|August 3, 2025
概括
严重的动脉样硬化,以高的阿加斯顿评分为标志,是直肠癌手术后高输出口腔 (HOS) 的重要危险因素. 这一发现表明,在患有晚期动脉样硬化症的患者中,应避免结石切除术,以预防脱水和功能障碍等并发症.
科学领域:
- 血管医学 血管医学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 在直肠癌切除后以防止泄漏为目的,结肠膜切除是常见的.
- 高输出口腔 (HOS) 是一种导致脱水和潜在功能障碍的并发症.
- 动脉样硬化被研究为HOS的潜在危险因素.
研究的目的:
- 评估通过Agatston得分量化的动脉样硬化,作为HOS的新风险因素.
- 检查阿加斯顿分数与直肠癌患者HOS发生之间的关联.
主要方法:
- 追溯性队列研究,对115名患有暂时结肠切除术的直肠癌患者进行.
- 使用在手术前CT扫描上的Agatston得分量化的大动脉化.
- 根据Agatston得分对患者进行分类,以分析HOS发生率.
主要成果:
- HOS发生在24.1%的患者中.
- 高的阿加斯顿得分与更高的HOS发病率显著相关 (P=0.01).
- HOS的独立风险因素包括高中性粒细胞与淋巴细胞的比率和高Agatston分数.
结论:
- 升高的阿加斯顿分数与HOS发育有关.
- 考虑在患有严重动脉硬化症的患者中避免结节切开,以减轻HOS风险.
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