抑郁症状和健康状况结果之间的关联在患有症状的外周动脉疾病的患者中
Francky Jacque1, Eman Mubarak1, Gaëlle Romain1
1Vascular Medicine Outcomes Program, Yale University, New Haven, CT, USA.
Journal of psychosomatic research
|August 3, 2025
概括
患有抑郁症状的外周动脉疾病 (PAD) 患者报告健康状况较差. 然而,健康状况在血管护理三个月内得到改善,无论抑郁症的严重程度如何,突出了综合护理的必要性.
科学领域:
- 血管医学 血管医学
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 抑郁症状在周围动脉疾病 (PAD) 中很常见,并且与不良结果有关.
- 了解抑郁症对PAD患者健康状况的影响对于有效管理至关重要.
研究的目的:
- 检查表现时抑郁症状与PAD特定健康状况结果之间的关联.
- 评估PAD患者12个月的健康状况轨迹,患者有不同程度的抑郁症状.
主要方法:
- 利用了来自PORTRAIT注册 (2011-2015) 的数据,包括患有新出现或恶化关节的患者.
- 通过外围动脉问卷 (PAQ) 评估健康状况,通过患者健康问卷 (PHQ-8) 评估抑郁症状.
- 采用混合重复测量模型和倾向匹配的队列分析来评估随时间和相互作用的健康状况变化.
主要成果:
- 在1272名PAD患者中,有36.8%出现轻度,中度或重度抑郁症状.
- 与没有症状的患者相比,患有严重抑郁症状的患者的PAQ得分在基线显著降低.
- 在三个月内,所有抑郁症严重程度的健康状况 (PAQ分数) 显著改善,随后稳定.
结论:
- 患有抑郁症状的PAD患者表现出较差的基线健康状况,但在开始血管护理后显示出类似的改善轨迹.
- 在三个月内观察到健康状况的改善,并持续下去,无论最初的抑郁症严重程度如何.
- 显然需要将抑郁症管理策略纳入常规的外周动脉疾病护理途径.
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