相关实验视频
Updated: Sep 13, 2025

10:42
A Free-breathing fMRI Method to Study Human Olfactory Function
Published on: July 30, 2017
9.7K
在巴西人口样本中,成年人嗅觉功能下降的患病率
Wilker Antunes Lira1, Gilmar Felisberto Junior1, Marco Aurélio Fornazieri2
1Faculdade de Medicina de Marília (FAMEMA), Marília, SP, Brazil.
Brazilian journal of otorhinolaryngology
|August 3, 2025
概括
嗅觉变化在40岁以上的成年人中非常普遍,特别是老年人. 每一年都会使嗅觉功能障碍的风险增加8%.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 嗅觉功能障碍是一种常见但往往未被诊断的疾病.
- 年龄是影响感官知觉的重要因素,包括嗅觉.
研究的目的:
- 确定40岁以上成年人未被诊断的嗅觉变化的患病率.
- 在这个人口群体中确定与嗅觉障碍相关的因素.
主要方法:
- 一项涉及284名成人和老年参与者的横截面研究,没有报告的鼻子问题.
- 用宾夕法尼亚大学的气味识别测试 (UPSIT) 和视觉模拟量表来评估嗅觉能力.
主要成果:
- 嗅觉变化的患病率很高:老年人中有96.9%,年轻人中有80.4%.
- 在老年人中,年龄和UPSIT分数之间存在显著的相关性 (Rho = 0.33,p < 0.001).
- 老年人患嗅觉障碍的患病率更高 (p < 0.001),年龄每年风险增加8%.
结论:
- 老年人群表现出更高的患病率和降低嗅觉的风险.
- 年龄是嗅觉功能障碍的关键预测因素,每年生命的风险增加8%.
相关概念视频
Olfactory Receptors: Location and Structure
9.6K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.6K
Olfaction
45.2K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
45.2K
Physiology of Smell and Olfactory Pathway
9.5K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
9.5K

