相关实验视频

Updated: Sep 13, 2025

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
08:41

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues

Published on: June 3, 2019

9.9K

Qsox1有助于血管重塑,以应对高血压

Malha Sadoune, Jérome Mourad, Céline Luc

    Journal of vascular research
    |August 3, 2025
    PubMed
    概括

    血管硫氧化酶 (QSOX1) 对于高血压中适应性动脉重塑至关重要. 失去QSOX1会损害血管光滑肌肉细胞的适应,导致心力衰竭和压力过载下的纤维化.

    更多相关视频

    Assessing Murine Resistance Artery Function Using Pressure Myography07:25

    Assessing Murine Resistance Artery Function Using Pressure Myography

    Published on: June 7, 2013

    22.4K
    A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology16:46

    A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

    Published on: June 3, 2014

    11.9K

    相关概念视频

    Hypertension II: Pathophysiology01:29

    Hypertension II: Pathophysiology

    Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
    78
    Hypertension and Regulation of Blood Pressure01:18

    Hypertension and Regulation of Blood Pressure

    Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
    3.1K
    Autoregulation of Blood Flow01:17

    Autoregulation of Blood Flow

    Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
    Chemical Signaling in Autoregulation
    Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....
    2.8K
    Regulation of Angiogenesis and Blood Supply01:24

    Regulation of Angiogenesis and Blood Supply

    Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
    2.7K
    Neural Regulation of Blood Pressure01:18

    Neural Regulation of Blood Pressure

    The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
    Baroreceptor Reflex
    Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
    3.4K
    Hormonal Regulation of Blood Pressure01:17

    Hormonal Regulation of Blood Pressure

    Endocrinal or hormonal intervention in the cardiovascular system is predominantly exerted by the catecholamines - epinephrine and norepinephrine, as well as a slew of hormones that interact with renal function to modulate blood volume.
    Epinephrine and Norepinephrine
    The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction...
    3.2K