全球伤寒发病率:一个更新的系统综述与元分析
Shruti Murthy1, Nienke N Hagedoorn1, Suzanne Faigan1
1Centre for International Health, University of Otago, Dunedin, New Zealand.
The Lancet. Infectious diseases
|August 3, 2025
概括
在全球范围内,伤寒发烧的发病率仍然很高,特别是在非洲和亚洲,以及幼儿中. 这些发现强调,迫切需要优先考虑风险人群的伤寒预防策略,包括疫苗.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 关于伤寒发病率的当代证据对于为公共卫生政策提供信息至关重要.
- 疫苗引入和非疫苗措施需要最新的发病率数据,以便有效的决策.
- 这项研究更新了先前对全球伤寒发病率的系统综述和元分析.
研究的目的:
- 提供全球伤寒发病率的最新系统审查和元分析.
- 为了为台风热的预防策略提供决策信息.
主要方法:
- 在2024年12月之前,对多个数据库和预版存储库进行了系统审查.
- 一个更新的元分析包括数据库创建时的研究和自2018年1月以来发布的新报告.
- 亚组分析和元回归研究了根据地区,年龄和研究质量的发病率变化.
主要成果:
- 更新的审查包括14份新报告,贡献了41个发病率估计.
- 在基于人群的研究中,新报告的聚合发病率为每10万人/年 (PYO) 206.3,在混合监测中为132.5 PYO.
- 发病率在南亚 (320.6 PYO) 和2至5岁以下的儿童 (159.6 PYO) 中最高.
结论:
- 伤寒发烧的发病率特别高在非洲和亚洲,在幼儿中.
- 这些发现强化了在这些地区和年龄组优先考虑防治伤寒的必要性,包括接种疫苗.
相关概念视频
Prevalence and Incidence
815
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
815
Patterns of Fever
3.0K
Before understanding the types and patterns of fever, it is essential to know its phases.
3.0K
Bias in Epidemiological Studies
683
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
683
Acute Pyelonephritis II: Diagnostic Studies and Management
40
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
40


