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部分切除术与细胞癌的皮肤切除术的长期结果:倾向匹配的分析
Madison Stamper1, Jennifer Collins2, Ronald S Arellano3
1Marshall University Joan C. Edwards School of Medicine, Huntington, WV.
Urology
|August 3, 2025
概括
部分切除术和图像导向切除显示,细胞癌 (RCC) 的10年生存率相似. 切除具有较低的程序风险,但更高的再干预率,指导患者特定的治疗选择.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 最少侵入性手术的方法
背景情况:
- 细胞癌 (RCC) 的治疗包括手术切除或切除.
- 部分切除术 (PN) 和图像导向切除术 (IGA) 是常见的治疗选择.
- 将PN与IGA的长期结果进行比较对于治疗选择至关重要.
研究的目的:
- 为了比较PN与RCC的IGA的过程前结果和长期 (10年) 结果.
- 评估PN和IGA之间的生存率,转移风险和重新干预率.
- 为RCC管理的临床决策提供信息.
主要方法:
- 使用多机构电子病历数据库 (TriNetX) 的回顾性队列研究.
- 包括经过PN,冷移除或基于热的移除 (2004-2025) 的RCC成年患者.
- 倾向分数匹配 (PSM) 均衡队列;使用卡普兰-梅尔曲线和千平方测试分析结果.
主要成果:
- 与减血相比,PN与更长的住院时间,ICU入院和输血有关.
- 废除显示显著更高的10年再干预率 (13.0%的冷废除,9.6%的基于热的废除) 与PN (1.3%).
- 在所有治疗组中,10年生存率相似 (87.8%-89.4%).
结论:
- 在RCC中,PN和皮切除提供了相似的10年生存率和转移控制.
- 废除手术导致立即发病率降低,但长期增加了重新干预的需要.
- 治疗决策应根据患者的并发症和手术风险进行个性化.
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