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双翻角肝脏T1映射与B1校正在3T - 在体外和体外评估评估
Kim Sivesgaard1, Rozh Al-Mashhadi1, Thomas Winther Buus2
1Department of Radiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.
双翻角 (DFA) T1映射显示了肝脏成像的优良线性,有较大的感兴趣区域 (ROI) 提高了准确性和 in vivo 的读者一致性. 这种技术提供了精确的肝脏T1测量.
科学领域:
- 放射学和医学成像学 医学成像学
- 量化MRI是指数量化的MRI.
- 肝胆道成像 肝胆道成像
背景情况:
- 准确的T1映射对于肝病评估至关重要.
- 双翻转角度 (DFA) T1映射为定量MRI提供了一个快速的方法.
- 优化感兴趣区域 (ROI) 选择是可靠体内测量的关键.
研究的目的:
- 为了评估3D全肝双翻角 (DFA) T1映射的体外精度和线性.
- 为了比较各种循环ROI采样策略在体内肝脏T1测量.
主要方法:
- 在3T时使用了3D稳定状态破坏的梯度回声与DFA.
- 在体外验证与反转回收旋回声 (IRTSE) 参考T1值相对应.
- 在体内对30名患者进行的研究,评估手动细分和4种ROI策略,以获得读者间一致.
主要成果:
- 在体外的DFA T1测量显示出强烈的线性 (R2=0.9912) 与IRTSE相比高估了16.33%.
- 在体内,更大的ROI区域改善了读者间协议 (R2增加到0.9601) 和与手动细分的协议.
- 增加ROI大小始终提高了准确性,并减少了两种读者的变化.
结论:
- DFA T1映射提供了一个高度线性和准确的方法来量化肝脏T1.
- 在体内选择更大的ROI显著提高了测量可靠性和一致性.
- DFA T1映射是量化肝脏MRI的一个有前途的技术.
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