物中多环芳的饮食暴露:来自尿路生物监测的证据
Pil Jun Yun1, Gyojin Choo2, Hanbyul Park2
1Department of Environmental Engineering, Seoul National University of Science and Technology, Seoul, 01811, Republic of Korea; Risk Assessment Team, Korean Institute of Product Safety, Seoul, 06771, Republic of Korea.
Environmental research
|August 3, 2025
概括
这项研究在狗粮和尿液中发现了多环芳 (PAHs),其中烯是最常见的. 非饮食暴露,而不是食物,是狗中PAH负担的主要来源.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 伴侣动物健康 动物健康
背景情况:
- 物与人类共享室内环境,引发了人们对它们暴露在多环芳 (PAH) 等环境污染物的担忧.
- 有限的数据存在于物暴露水平的PAHs,需要研究了解他们的毒理负担.
研究的目的:
- 通过分析配对的狗粮和尿液样本,对狗的多环芳 (PAH) 暴露进行调查.
- 确定伴侣犬中PAH暴露的水平,分布和主要来源.
主要方法:
- 分析了47个商业干颗粒狗粮样本和相应的狗尿样,以检测多环芳 (PAH) 和其代谢物.
- 量化总PAH和特定代谢物,将食物度与尿中的代谢物水平和体重相关联.
主要成果:
- 在所有狗粮和尿液样本中检测到多环芳 (PAH) 和其代谢物,其中纳夫他林及其氧化代谢物占主导地位.
- 狗的尿液PAH代谢物度与韩国的人类水平相当.
- 虽然饮食摄入与尿路代谢物相关,但它仅占每日总摄入量的1.57%,表明非饮食来源占主导地位.
结论:
- 非饮食暴露途径是狗中多环芳 (PAH) 负担的主要来源.
- 对物环境PAH暴露路径进行进一步的研究是有必要的.
- 调查结果强调,由于共享生活空间,在环境健康评估中考虑物的重要性.
关键词:
每日摄入量 每日摄入量狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗食物 食物 食物 食物代谢产物的代谢物多环芳香碳化合物 多环芳香碳化合物尿液 尿液 尿液更多相关视频
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