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Updated: Sep 13, 2025

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针对Cas12a非目标歧视的动力基础

Yuyoung Kim1, You Hee Choi2, Minji Kim1

  • 1Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591; Department of Medical Sciences, Graduate School of The Catholic University of Korea, Seoul 06591, Korea.

BMB reports
|August 4, 2025
PubMed
概括

克里斯普尔-Cas12a基因编辑表现出高特异性,因为它对种子区域的DNA不匹配敏感,这控制了R循环形成和裂变效率.

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