年龄对大动脉根置换的影响
Elizabeth L Norton1, Parth M Patel1, Dov Levine2
1Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, 1365 Clifton Road NE, Suite A 2213, Atlanta, GA 30322, United States.
概括
大动脉根置换在成人年龄范围内是可行的,但对于80岁及以上的患者来说,结果和存活率明显更差. 对接受这种手术的老年患者来说,仔细的风险效益分析至关重要.
科学领域:
- 心血管外科心血管外科
- 胸部外科手术 胸部外科手术
- 大动脉外科手术
背景情况:
- 大动脉根置换是大动脉根和门病理学的常见手术.
- 对大动脉根置换的年龄分层结果尚未得到充分确立.
研究的目的:
- 根据患者年龄分层地检查大动脉根置换的短期和长期结果.
主要方法:
- 从2004年到2021年接受大动脉根置换的2748名成年患者的回顾性分析.
- 患者被分为18至80岁的年龄组.
- 分析了包括中风,并发症,重新手术和生存在内的结果.
主要成果:
- 80岁以上的年龄组中,中风发生率 (9.7%) 和住院死亡率 (13%) 显著上升.
- 年龄较大的患者 (≥80) 患有更多并发症,住院时间更长,10年生存率更差 (49%).
- 在30-39岁 (7.3%) 和40-49岁 (5.8%) 的年龄组中,再操作率最高.
结论:
- 大动脉根置换在所有成年人中都是可能的,结果可以接受.
- 在80岁及以上的患者中,手术结果和长期存活率明显下降.
- 在70岁以上的患者考虑主动脉根置换时,一个关键的风险:益处分析是必不可少的.
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