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Updated: Sep 13, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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具有两种不同的结合点的水溶性体,用于强大的ATP化

Nicole Vorobyov1, Galia Maayan1

  • 1Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Technion City, Haifa, 3200008, Israel.

Chemistry (Weinheim an der Bergstrasse, Germany)
|August 4, 2025
PubMed
概括

研究人员开发了新的类化合物,它结合了两种策略来抑制腺三酸盐 (ATP) 结合. 这些强大的ATP合剂比现有方法具有明显更高的结合亲和力,提供了新的治疗潜力.

关键词:
结合ATP与ATP的结合方式双重结合的双重结合激酶激酶是一种激素.这是一种类类.基酸是基酸中的一种.类特皮里丁的使用.

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