一个简单的nomogram预测模型,用于女性癌症幸存者怀孕意图
Qin Xie1, Qipeng Wei1, Yanan Zhu1
1Department of Obstetrics and Gynecology, Xiangyang Central Hospital, The Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, Hubei, People's Republic of China.
The journal of obstetrics and gynaecology research
|August 4, 2025
概括
年轻的女性癌症患者.
科学领域:
- 生殖健康 生殖健康
- 在瘤学瘤学.
- 生物统计学 生物统计学
背景情况:
- 癌症诊断显著影响年轻女性的生殖健康决策.
- 生育能力的维护是生育年龄癌症幸存者的关键问题.
研究的目的:
- 在癌症诊断后确定影响生育意向的因素.
- 开发一种预测模型,用于识别希望在未来分娩的女性.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) 的数据.
- 包括50岁或更年轻的女性被诊断患有癌症.
- 采用了后勤回归,并构建了一个用于预测的名ogram.
主要成果:
- 诊断时的年龄和之前的活产是怀孕意向的重要预测因素.
- 纳入这些因素的名图实现了曲线下的面积 (AUC) 为0.9312.
- 单变量分析显示了与并发症和社会经济因素的关联,但这些在多变量模型中没有显著意义.
结论:
- 癌症诊断时的年龄和活产史是生殖意图的关键决定因素.
- 开发的诺米图准确地识别出患有生育欲望的患者,帮助个性化治疗和生育保护计划.
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