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Updated: Sep 13, 2025

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
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Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

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在原生结构生物学中推进灵敏度和特异性极限:

Kumar Tekwani Movellan1,2, Daniel Banks3, Christian Reiter4

  • 1Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.

Journal of the American Chemical Society
|August 4, 2025
PubMed
概括

这项研究引入了一种高度敏感的-19核磁共振方法,用于分析哺乳动物细胞中的蛋白质结构. 这种动态核极化 (DNP) 方法使得我们能够在细胞环境中对像环素A这样的蛋白质进行原子层次的结构洞察.

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