鼻黄金葡萄球菌隔离和COVID-19患者的细菌培养档案:基于肺部参与的比较研究
Burcu Vural Camalan1, Naciye Badir2, Sumeyra Doluoglu1
1Department of Otorhinolaryngology Head and Neck Surgery, University of Health Sciences Ankara Etlik City Hospital, Ankara, TUR.
Cureus
|August 4, 2025
概括
在COVID-19患者中,鼻黄金葡萄球菌的携带与肺部参与或不参与并没有显著差异. 细菌资料也显示,与COVID-19状态没有显著的关联,这表明临床相关性不清楚.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 鼻甲状腺携带金黄色葡萄球菌是常见的.
- COVID-19可能会影响呼吸系统,可能会改变鼻微生物组.
- 了解COVID-19中的细菌共感染或殖民对于患者管理至关重要.
研究的目的:
- 为了确定COVID-19患者的黄金葡萄球菌携带率.
- 在COVID-19患者中描述其他可培养细菌.
- 评估COVID-19患者的细菌生长模式是否不同,是否涉及肺部.
主要方法:
- 鼻样本从COVID-19患者 (有/没有肺部参与) 和PCR阴性对照中收集.
- 胸部CT扫描评估了肺部的参与.
- 进行了细菌培养,以确定物种和量化携带.
主要成果:
- 黄金葡萄球菌在21.6%的COVID-19患者和35.7%的对照人群中被分离出来.
- 在COVID-19患者与无肺部感染之间,没有观察到S. aureus携带的显著差异.
- 总体细菌概况在COVID-19状态或肺部参与组之间没有显著差异.
结论:
- 鼻黄金菌殖民和细菌分布与COVID-19状态没有显著的关联.
- 肺部参与COVID-19并没有改变S. aureus携带或细菌概况.
- 在COVID-19早期S. aureus殖民的临床相关性需要进一步调查.
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