对比介质类型对皮肤冠状动脉干预 (PCI) 中功能的影响:考虑对比介质体积和手术前功能的倾向性得分匹配分析
Tomokazu Takeuchi1,2, Mashio Koike1, Yuko Seki1
1Radiology, Gunma University Hospital, Maebashi, JPN.
Cureus
|August 4, 2025
概括
这项研究发现,在经皮冠状动脉干预 (PCI) 后接受IOHEXOL或IOMEPROL对比剂的患者之间,通过估计的球过率 (eGFR) 测量功能没有显著差异. 这两种对比剂在术后的功能方面表现出类似的安全性.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 放射学 放射学是一门学科.
背景情况:
- 对比诱导的脏病是皮肤穿冠状动脉干预 (PCI) 后的一个担忧.
- 常用的是像iohexol和iomeprol这样的低度对比介质 (LOCM),但它们对的影响的比较需要评估.
研究的目的:
- 为了比较iohexol与iomeprol对接受PCI的患者功能的影响.
- 使用这两种LOCM来评估PCI后估计的膜过率 (eGFR) 的变化.
主要方法:
- 180名接受PCI (2021年1月至2022年12月) 的患者的回顾性分析.
- 倾向性得分匹配创造了两个组 (每组44名患者),接受IOHEXOL或IOMEPROL.
- 在PCI后24小时和>72小时对eGFR的评估变化.
主要成果:
- 两组之间基线特征 (年龄,性别,eGFR,对比度量) 没有显著差异.
- 在PCI后24小时或>72小时,绝对或相对eGFR变化没有显著差异.
- 24小时后EGFR的平均相对变化:1.6% (iohexol) 与1.1% (iomeprol) 相比. 平均相对eGFR变化>72小时: -2.1% (iohexol) 与 -0.3% (iomeprol) 相比.
- 在任何一组中都报告了零例对比后急性损伤.
结论:
- 在PCI后,IOhexol和IOmeprol在功能方面表现出相似的安全概况.
- 两种LOCM都没有在这种患者队列中在保护eGFR方面显著的优势.
- 关于在PCI中使用iohexol或iomeprol的临床决定可能不需要基于不同的功能结果.
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