相关实验视频

Updated: Sep 13, 2025

Quantitative Analysis of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Stabilization in a Neural Model of Alzheimer's Disease (AD)
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Quantitative Analysis of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Stabilization in a Neural Model of Alzheimer's Disease (AD)

Published on: January 10, 2025

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调节失调通过干扰AMPK/Drp1通路来破坏线粒体平衡,从而加剧斑块的进展和不稳定性

Pingping Hu1, Mengmeng Liu2, Tongtong Wu2

  • 1Chongqing Key Laboratory for Pharmaceutical Metabolism Research, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China.

Theranostics
|August 4, 2025
PubMed
概括

在大动脉细胞中,sarcoplasmic/endoplasmic网膜 ATPase 2 (SERCA2) 功能障碍通过AMPK/Drp1通路破坏线粒体功能,加速动脉样硬化. 向AMPK或Drp1可以治疗斑块脆弱性.

关键词:
这就是AMPKK.这就是 SERCA2 的原因.动脉样硬化 动脉样硬化线粒体中的线粒体.斑块的稳定性 斑块的稳定性

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