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Updated: Sep 13, 2025

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在不同的瘤类型中,CD8 T细胞识别的新抗原的特性

S L C Ketelaars1, M M van Buuren1, A Gangaev1

  • 1Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Immuno-oncology technology
|August 4, 2025
PubMed
概括

对新抗原免疫性进行计算预测对于癌症免疫疗法至关重要. 这项研究表明,解解联体得分和HLA结合亲和力是各种瘤类型的关键预测因素,指导未来的免疫疗法开发.

关键词:
CD8 T细胞的识别能力结合HLA的亲缘关系解的连接体得分得分.免疫占主导地位的层次结构.新抗原免疫性新抗原免疫性.在pHLA的多重屏幕上.

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