童年不良经历与神经发育障碍之间的相互作用:对最近证据的系统审查
Reema Jangid1, Naga Seema1, Gourab Arun2
1Centre for Psychology, School of Medical Sciences, University of Hyderabad, Telangana, India.
Annals of neurosciences
|August 4, 2025
概括
儿童不良经历 (ACE) 与神经发育障碍 (NDD) 有关. 这篇评论证实了ACE和NDD (如ADHD,ASD和认知障碍) 之间的剂量反应关系.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 儿童不良经历 (ACE) 越来越多地被认为对神经发育障碍 (NDD) 的影响.
- 有限的研究专门讨论了ACE在ADHD,ASD和认知障碍的发病,严重程度和进展中的独特作用.
- 了解早期生活逆境和神经发育之间的复杂相互作用对于有针对性的干预至关重要.
研究的目的:
- 系统地审查和批判地总结有关ACE和NDD之间关系的现有研究.
- 评估当前关于ACE和NDD相互依存性的知识.
- 确定文献上的差距,并提出未来的研究方向和临床应用.
主要方法:
- 使用PECO和PRISMA框架在四个主要数据库 (ScienceDirect,科学网,EBSCO,PubMed) 进行系统的文献搜索.
- 包括32项符合预定义标准的研究,使用MERSQI和CASP进行质量评估.
- 批判性评估ACE和特定NDD之间的相互作用:多动症,自闭症和认知障碍.
主要成果:
- 审查发现了强有力的经验证据,支持ACE和NDD之间的一致的双向,周期性和剂量反应相关性.
- 大多数被纳入的研究质量中等至高,表明了可靠的发现.
- 这些发现突显了早期生活逆境对神经发育轨迹的普遍影响.
结论:
- ACEs显著影响NDD的发展,严重程度和进展,包括ADHD,ASD和认知障碍.
- 需要高质量的研究,采用不同的方法,以进一步阐明ACE和NDD之间的动态相互作用.
- 未来的研究应该为受ACE和NDD影响的个体设计有效干预措施.
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