人工智能和机器学习在疫苗和免疫疗法开发中的作用 - - 昨天,今天和明天
Elhoucine Elfatimi1, Yassir Lekbach1, Swayam Prakash1
1Laboratory of Cellular and Molecular Immunology, College of Medicine, The Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, United States.
Frontiers in artificial intelligence
|August 4, 2025
概括
人工智能 (AI) 和深度学习 (DL) 正在彻底改变疫苗和免疫治疗的发展. 这些技术加速了研究,提高了准确性,并减少了对动物试验的依赖,以获得更快,针对疾病和癌症的个性化治疗.
科学领域:
- 医学科学 医学科学 医学科学
- 免疫学 免疫学 免疫学
- 计算生物学 计算生物学
背景情况:
- 疫苗和免疫治疗的开发是医学的一个重大成就.
- 亚单位疫苗提供优势,但开发成本高,耗时长.
- 传统方法依赖于广泛,昂贵和耗时的体内试验.
研究的目的:
- 审查AI和DL在疫苗和免疫疗法研究中的应用.
- 突出AI/DL作为时间和资源高效的战略.
- 讨论AI/DL在精密疫苗学中的未来挑战和机遇.
主要方法:
- 人工智能和DL用于预测框架和数据驱动的决策.
- 计算模型,系统疫苗学和多omics数据的整合.
- 人工智能/DL有助于患者分层,个性化治疗设计和表位选择.
主要成果:
- AI/DL增强了决策,患者分类和疫苗和免疫治疗的目标选择.
- 这些技术提高了对免疫调节和免疫规避的理解.
- AI/DL促进了针对传染病和癌症的定制疫苗和免疫治疗药物的开发.
结论:
- 人工智能和DL正在改变疫苗和免疫治疗研究.
- 这些技术有可能取代动物试验并改善临床试验.
- 人工智能/DL为快速开发精确和个性化的疫苗和免疫疗法铺平了道路.
相关概念视频
Microorganisms in Medicine and Therapeutics
337
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
337
Cancer Vaccines
510
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
510
Vaccinations
45.3K
Overview
45.3K
Tumor Immunotherapy
660
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
660
Issues And Trends In Healthcare Delivery System
5.8K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.8K
Immunological Memory
5.0K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
5.0K


