在新西兰人口中估计正常和参考脉冲波速度
Ekta Dahiya1, Andrew Lowe1, Rita Krishnamurthi2
1Institute of Biomedical Technologies (IBTec), Auckland University of Technology, Auckland, New Zealand.
Journal of the Royal Society of New Zealand
|August 4, 2025
概括
这项研究确定了新西兰成年人的正常脉冲波速度 (PWV) 值,发现年龄和血压是关键预测因素. PWV值低于国际标准,并因种族而异.
科学领域:
- 心血管生理学心血管生理学
- 血管衰老 血管衰老
- 生物医学工程 生物医学工程
背景情况:
- 脉冲波速度 (PWV) 是动脉硬和心血管风险的标志物.
- 确定人群特异性PWV的参考值对于准确的风险评估至关重要.
- 之前的研究还没有全面评估新西兰人口中的PWV.
研究的目的:
- 在新西兰成年人群中确定正常和参考脉冲波速度 (PWV) 值.
- 调查PWV和心血管风险因素之间的关系,包括年龄,血压和种族.
- 将新西兰PWV值与国际标准进行比较.
主要方法:
- 对120名年龄在18岁以上的成年人进行了一项观察性横截面研究.
- 参与者被分为年龄组和血压 (BP) 类别.
- 使用多普勒超声波测量PWV通过带-关节方法.
主要成果:
- 研究群体的PWV平均值为5.88 ± 1.49 m/s.
- 随着年龄的增长,PWV显著增加,在参考值人口 (RVP) 组中更高.
- 在欧洲和非欧洲人口之间观察到PWV平均值的显著差异 (p = 0.004).
- 年龄和平均血压是PWV最强的预测因素,解释了54.5%的变化.
结论:
- 新西兰成年人PWV值通常低于国际标准.
- 在这个人群中,年龄和平均血压是PWV的主要决定因素.
- 种族是影响PWV的一个重要因素,突出了对人口特定评估的需要.
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