从10岁到40岁的父母收入和精神疾病:一个基因信息化的人口研究
Hans Fredrik Sunde1,2,3, Espen Moen Eilertsen4, Jonas Minet Kinge1,5
1Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
父母收入较低与后代精神疾病增加有关,社会因果关系在青春期起作用,社会选择在成年期占主导地位. 这项研究分析了整个10-40岁的挪威人口.
科学领域:
- 精神病学是一个精神病学.
- 遗传学 遗传学 是一个
- 社会学 社会学 社会学
背景情况:
- 父母收入较低与后代患精神疾病的比率较高有关.
- 父母收入和后代精神健康之间的关系受到争论,社会因果关系和社会选择作为相互竞争的解释.
- 之前的研究产生了相互矛盾的结果,可能是由于研究后代年龄组的变化.
研究的目的:
- 在大量人口中,研究不同年龄段的父母收入和精神疾病之间的关联.
- 在收入-精神疾病关系中区分社会因果关系和社会选择.
- 检查表型,遗传和环境传播对这种协会的贡献.
主要方法:
- 利用了整个挪威10-40岁人口 (2006-2018) 的数据,将税收和健康登记簿联系起来.
- 根据年龄,性别和家长收入等级分析了精神疾病的患病率.
- 将基于亲属关系的模型应用于兄弟姐妹和双胞胎,将亲子关系分解为青春期,早期成年期和成年期的传播组件.
主要成果:
- 较低的父母收入排名与所有研究年龄段 (10-40岁) 大多数精神疾病的更高患病率相关.
- 任何精神疾病的患病率都随着年龄的增长而下降,当比较父收入四分位数的顶部和底部时.
- 现型传播显著解释了青春期的亲子相关性,但不是成年期,而遗传和环境因素在所有年龄段都有所贡献.
结论:
- 研究结果表明,社会因果关系在青春期精神疾病中起着重要作用.
- 社会选择完全解释了成年时精神疾病的父母后代相关性.
- 社会经济地位对心理健康的影响在不同发育阶段有很大差异.
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